Author’s response to reviews Title: Changes in CT morphology can be an independent response marker for patients receiving regorafenib for colorectal liver metastases: retrospective pilot study Authors:
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Early morphological change for predicting outcome in metastatic colorectal cancer after regorafenib
Background and Objective It is unclear whether early morphological change (EMC) is a predictive marker for regorafenib in metastatic colorectal cancer (mCRC). Therefore, the present study investigated whether EMC can predict the outcome of mCRC patients receiving regorafenib. Results This study evaluated 68 patients. Among 52 patients with lung metastasis, 16 (31%) had cavity formation (CF). ...
متن کاملRadiological imaging markers predicting clinical outcome in patients with metastatic colorectal carcinoma treated with regorafenib: post hoc analysis of the CORRECT phase III trial (RadioCORRECT study)
OBJECTIVE To identify imaging markers predicting clinical outcomes to regorafenib in metastatic colorectal carcinoma (mCRC). METHODS The RadioCORRECT study is a post hoc analysis of a cohort of patients with mCRC treated within the phase III placebo-controlled CORRECT trial of regorafenib. Baseline and week 8 contrast-enhanced CT were used to assess response by RECIST 1.1, changes in the sum ...
متن کاملDynamic Contrast-Enhanced Ultrasound of Colorectal Liver Metastases as an Imaging Modality for Early Response Prediction to Chemotherapy
Our aim was to investigate whether dynamic contrast-enhanced ultrasound (DCE-US) can detect early changes in perfusion of colorectal liver metastases after initiation of chemotherapy. Newly diagnosed patients with colorectal cancer with liver metastases were enrolled in this explorative prospective study. Patients were treated with capecitabine or 5-fluorouracil-based chemotherapy with or witho...
متن کاملEffect of saffron on liver metastases in patients suffering from cancers with liver metastases: A randomized, double blind, placebo-controlled clinical trial
Objective: Cancer represents the second cause of mortality in the world. Saffron as a medicinal plant is known for its anti-cancer and anti-depressant properties. In this randomized double blind clinical trial, the effects of saffron on response to treatment in patients suffering from liver metastasis were evaluated. Materials and Methods: Thirteen patients suffering from liver metastases who r...
متن کاملAuthor’s response to reviews Title: Effectiveness of Direct-Acting Antiviral Therapy for Hepatitis C in Difficult-to-Treat Patients in a Safety-Net Health System: A Retrospective Cohort Study Authors:
Title: Effectiveness of Direct-Acting Antiviral Therapy for Hepatitis C in Difficult-to-Treat Patients in a Safety-Net Health System: A Retrospective Cohort Study Authors: Christina Yek ([email protected]) Carolina de la Flor ([email protected]) John Marshall ([email protected]) Cindy Zoellner ([email protected]) Grace Thomphson ([email protected]) Lisa Quirk (lis...
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تاریخ انتشار 2018